ligand design

How Do Ligands Influence Catalysis?

Ligands can influence catalysis in several ways:
Electronic Effects: Ligands can donate or withdraw electron density from the metal center, affecting its reactivity.
Steric Effects: The size and shape of ligands can influence the accessibility of the active site and the spatial arrangement of substrates.
Stability: Ligands can stabilize the metal center, preventing deactivation of the catalyst.
Solubility: Ligands can enhance the solubility of the catalyst in the reaction medium, improving its efficiency.

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