solvent compatibility

How can solvent-free conditions be advantageous in catalysis?

Solvent-free conditions eliminate the need for solvents altogether, which can simplify the reaction setup, reduce costs, and minimize waste. This approach can also prevent potential solvent-related issues such as catalyst deactivation or undesired side reactions. Solvent-free catalysis is particularly advantageous in solid-phase or gas-phase reactions, where the catalyst and reactants can interact directly without a solvent medium.

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