Can Catalysis in the Liver be Enhanced or Inhibited?
Yes, catalysis in the liver can be modulated. Certain substances known as inducers can enhance the activity of liver enzymes, while inhibitors can reduce their activity. For example, chronic alcohol consumption can induce the activity of some cytochrome P450 enzymes, leading to faster metabolism of certain drugs. Conversely, grapefruit juice contains compounds that inhibit specific cytochrome P450 enzymes, potentially leading to increased drug concentrations and adverse effects.
