Are There Challenges Associated with Deprotonation in Catalysis?
While deprotonation is a useful tool in catalysis, it also presents challenges. For instance, the presence of competing bases or acids in the reaction mixture can complicate the deprotonation step. Additionally, overly strong bases can lead to unwanted side reactions or decomposition of the catalyst. Therefore, careful optimization of reaction conditions and the choice of catalysts or bases is crucial for successful catalytic processes involving deprotonation.