There are several reasons to consider substrate modification in catalysis:
Increased Reactivity: Modifying the substrate can make it more reactive, thereby enhancing the overall reaction rate. Improved Selectivity: Altering the substrate can lead to a more selective reaction, producing fewer by-products. Enhanced Compatibility: Some substrates may not naturally interact well with certain catalysts; modification can improve compatibility. Reduction of Inhibition: Certain functional groups in a substrate may inhibit the catalyst; modifying these groups can alleviate inhibition.
