Why is Ligand Coordination Important in Catalysis?
The coordination of ligands to a metal center can significantly impact the catalytic activity and selectivity in several ways:
Stabilization of Reactive Intermediates: Ligands can stabilize reactive intermediates, making it easier for the catalytic cycle to proceed. Modulation of Electronic Properties: Ligands can alter the electronic environment of the metal center, thus tuning its reactivity. For example, phosphine ligands are known for their ability to donate electron density to the metal center. Influence on Steric Environment: The spatial arrangement of ligands around the metal center can affect the access of substrates to the active site, thereby influencing the selectivity of the catalytic process.
