The use of safer chemicals in catalysis is critical due to several reasons: 1. Health and Safety: Reducing hazardous chemicals minimizes exposure risks to workers and consumers. 2. Environmental Impact: Safer chemicals help prevent pollution and reduce the ecological footprint of chemical processes. 3. Regulatory Compliance: Many regions have stringent regulations that require the use of less hazardous substances. 4. Economic Benefits: Reducing waste and hazards can lower costs associated with waste disposal and regulatory compliance.