Why Are Protein Complexes Important for Catalysis?
Protein complexes are essential for several reasons:
1. Enhanced Catalytic Efficiency: The spatial arrangement of active sites within a complex can lead to more efficient substrate binding and product release. 2. Regulation: Protein complexes allow for intricate regulation of catalytic activity, which is crucial for maintaining cellular homeostasis. 3. Substrate Channeling: Some complexes facilitate substrate channeling, where intermediates are passed directly from one enzymatic site to another, minimizing diffusion losses and increasing reaction rates.