What Techniques Are Used to Study Protein Complexes?
Understanding the structure and function of protein complexes requires advanced techniques:
1. X-ray Crystallography: This technique provides high-resolution structures of protein complexes, revealing the arrangement of subunits and active sites. 2. Cryo-Electron Microscopy (Cryo-EM): Cryo-EM allows for the visualization of protein complexes in their native state without the need for crystallization. 3. Nuclear Magnetic Resonance (NMR) Spectroscopy: NMR is used to study the dynamics and interactions within protein complexes.