thiamine pyrophosphate

Which Enzymes Use TPP as a Coenzyme?

Several key enzymes utilize TPP as a coenzyme. These include:
Pyruvate dehydrogenase complex - Catalyzes the conversion of pyruvate to acetyl-CoA.
Alpha-ketoglutarate dehydrogenase complex - Involved in the citric acid cycle, converting alpha-ketoglutarate to succinyl-CoA.
Transketolase - Participates in the pentose phosphate pathway, transferring two-carbon groups.

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