What Role Does Catalysis Play in Recombinant Glucocerebrosidase Activity?
The function of glucocerebrosidase is inherently catalytic. As an enzyme, it lowers the activation energy required for the hydrolysis of glucocerebroside. This catalytic action is essential for maintaining the proper balance of sphingolipids in the body. In recombinant glucocerebrosidase, maintaining the enzyme’s catalytic activity during production and storage is critical to its therapeutic efficacy.