What is the structure of 2-Deoxyribose 5-Phosphate Aldolase?
The structure of DERA is typically composed of a homodimer, where each monomer consists of approximately 259 amino acids. The active site of the enzyme contains a lysine residue, which is critical for its catalytic activity. The binding of the substrate to the active site induces a conformational change, facilitating the cleavage of the carbon-carbon bond in 2-deoxyribose-5-phosphate.
