What are the challenges associated with DERA-based catalysis?
Despite its advantages, there are some challenges associated with DERA-based catalysis. One of the primary challenges is the enzyme's sensitivity to various environmental factors, such as temperature and pH, which can affect its activity and stability. Additionally, the substrate specificity of DERA can be limited, necessitating the use of enzyme engineering to expand its substrate range. Furthermore, the large-scale application of DERA requires efficient production and purification methods, which can be technically demanding and costly.
