What is the role of cofactors in MTHFR-catalyzed reactions?
Cofactors such as FAD (flavin adenine dinucleotide) are essential for the proper function of MTHFR. FAD acts as an electron carrier during the reduction process, facilitating the catalytic activity of the enzyme. The availability and binding of cofactors are critical for the optimal performance of MTHFR and the subsequent downstream metabolic processes.
