Electrospray Ionization (ESI) is a technique used in mass spectrometry to produce ions from large molecules, such as proteins and polymers, which are otherwise challenging to ionize. ESI operates by applying a high voltage to a liquid to create an aerosol, which is then analyzed in the mass spectrometer. This method is gentle and preserves the integrity of the analyte, making it ideal for studying complex biological molecules and catalytic processes.
