Aldehyde dehydrogenase (ALDH) is a family of enzymes crucial for the metabolism of aldehydes. These enzymes catalyze the oxidation of aldehydes into carboxylic acids, a critical step in the detoxification of a variety of endogenous and exogenous aldehydes. The reaction involves the conversion of the aldehyde group (-CHO) into a carboxyl group (-COOH), typically utilizing NAD+ or NADP+ as a cofactor.
