What Information Can Spin-Spin Coupling Constants Provide?
- Bond Connectivity: J-coupling constants can indicate which atoms are directly bonded. - Dihedral Angles: Vicinal coupling constants (3J) can provide information about dihedral angles between atoms, helping to elucidate the three-dimensional structure. - Electronic Environment: The magnitude of J-coupling can be affected by the electronic environment, offering insights into the electron density and the presence of conjugation or aromaticity. - Dynamic Processes: Changes in J-coupling constants over time can indicate dynamic processes such as conformational changes or chemical exchange.
