The most commonly used catalysts in Reppe vinylation are transition metal complexes. Nickel catalysts, such as nickel carbonyl (Ni(CO)₄), are highly effective. Cobalt-based catalysts, like cobalt carbonyl (Co₂(CO)₈), are also frequently employed. These catalysts are chosen because of their ability to activate the acetylene and facilitate its addition to the carbonyl compound. Ligands such as phosphines or bipyridines are often used to stabilize the metal center and enhance the catalyst's performance.
