While TST has been instrumental in advancing our understanding of catalysis, it has limitations:
1. High-Energy Approximations: TST assumes that only high-energy states contribute to the reaction rate, which may not always be accurate. 2. Single Transition State: It simplifies the reaction pathway to a single transition state, ignoring possible multiple intermediate states. 3. Ideal Conditions: TST often assumes ideal conditions, which may not be applicable in all real-world scenarios.
