Despite their advantages, PFRs also have limitations: 1. Idealization: The plug flow model is an idealization that may not accurately represent real flow conditions, especially in the presence of axial dispersion or channeling. 2. Complexity in Multi-phase Systems: In systems involving multiple phases (e.g., gas-solid or liquid-solid), achieving true plug flow can be challenging due to interactions between phases. 3. Maintenance: The elongated design of PFRs can make maintenance and cleaning more difficult compared to other reactor types.