What are the Challenges of Using 1H NMR in Catalysis?
While 1H NMR is a valuable tool, it also has some limitations and challenges:
Sensitivity: The sensitivity of 1H NMR may be insufficient for detecting low-concentration species or intermediates. Complex mixtures: Catalytic reactions often produce complex mixtures, making it difficult to resolve overlapping signals. Paramagnetic species: Catalysts containing paramagnetic metals can broaden NMR signals, complicating spectral interpretation. Sample preparation: Preparing homogeneous samples without impurities is crucial for accurate NMR analysis.
