What are the Challenges in Using NMR for Catalysis Research?
One of the major challenges in using NMR for catalysis research is the sensitivity limitation. Detecting low-concentration intermediates or species in a complex mixture can be difficult. Another challenge is the need for isotopic labeling, especially for studying the mechanisms involving light elements like hydrogen. Additionally, the interpretation of NMR data requires a thorough understanding of both NMR theory and the catalytic system under study.