What are the Challenges in Using Catalysis for SARS-CoV-2 Treatment?
While catalysis offers many advantages, there are challenges in applying it to SARS-CoV-2 treatment:
Viral Mutations: SARS-CoV-2 can mutate, potentially leading to drug resistance. Catalysts designed to target specific viral proteins must be adaptable to these changes. Selectivity: Catalytic inhibitors must be selective for viral enzymes to avoid off-target effects on human enzymes, which could lead to toxicity. Stability and Activity: Catalytic inhibitors need to be stable and active in the human body to be effective. This requires careful optimization of their chemical properties.
