What Are the Challenges in Supramolecular Catalysis?
Despite their advantages, supramolecular catalysts also face several challenges:
Stability: The non-covalent interactions that hold supramolecular structures together are generally weaker than covalent bonds, potentially leading to stability issues under harsh reaction conditions. Scalability: The synthesis and assembly of supramolecular catalysts can be complex and costly, posing challenges for large-scale applications. Complexity: The design and optimization of supramolecular catalysts require a deep understanding of both the chemistry and the physical interactions involved, making the research and development process intricate.
