Despite its importance, interface science in catalysis faces several challenges:
1. Complexity of Real Catalysts: Real-world catalysts are often complex, with multiple active sites and phases, making it difficult to study and understand their interfaces. 2. Dynamic Nature: Interfaces can undergo changes during reactions, such as restructuring or poisoning, complicating their study. 3. Scale of Observation: Observing and manipulating interfaces at the atomic or molecular scale requires sophisticated and often expensive equipment.