Despite its advantages, fine tuned regulation faces several challenges: - Complexity: The catalytic process can be highly complex, involving multiple steps and intermediates, making it difficult to control. - Scalability: Techniques that work well in the lab may not be easily scalable to industrial levels. - Cost: Implementing precise control mechanisms can be expensive, requiring sophisticated equipment and materials. - Time-Consuming: Achieving the desired level of control often involves extensive trial and error.