Despite its significance, chiral catalysis faces several challenges:
1. Cost: Many chiral catalysts, especially those involving rare metals or complex ligands, can be expensive. 2. Scalability: Translating lab-scale reactions to industrial-scale processes can be challenging. 3. Selectivity: Achieving high enantioselectivity consistently can be difficult, especially for complex molecules. 4. Recycling: The reuse of chiral catalysts without loss of activity and selectivity is an ongoing challenge.
