What are the Challenges and Limitations of SMFM in Catalysis?
Despite its advantages, SMFM has some limitations. The need for fluorescent labeling can sometimes alter the properties of the molecules being studied. Additionally, the high sensitivity of SMFM makes it susceptible to photobleaching and background noise, which can affect the accuracy of measurements. Moreover, the technique requires sophisticated equipment and expertise, which can be a barrier for some research groups.
