What are the Advantages of Sharpless Asymmetric Epoxidation?
1. High Enantioselectivity: The reaction produces epoxides with high enantiomeric excess (often >90% ee). 2. Mild Reaction Conditions: The reaction typically occurs at room temperature and under mild conditions, making it practical for various substrates. 3. Wide Substrate Scope: Can be applied to a broad range of allylic alcohols, making it versatile for different synthetic applications. 4. Scalability: The reaction can be scaled up for industrial applications without significant loss of enantioselectivity or yield.
