What are some key applications of NHCs in Catalysis?
NHCs have been employed in a variety of catalytic processes, including:
- Cross-Coupling Reactions: NHCs are widely used in palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings. - Olefin Metathesis: NHCs serve as ligands in ruthenium-based catalysts for olefin metathesis reactions, which are crucial in the synthesis of complex organic molecules. - Hydrogenation: They are used in iridium and ruthenium catalysts for hydrogenation reactions, enabling the conversion of alkenes and alkynes to saturated hydrocarbons. - Carbene Transfer Reactions: NHCs facilitate carbene transfer reactions, which are important in the formation of C-C and C-H bonds.
