What Are Some Examples of Selenoproteins Involved in Catalysis?
Several selenoproteins are well-known for their catalytic activities:
- Glutathione Peroxidases (GPx): These enzymes protect cells from oxidative damage by reducing hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. - Thioredoxin Reductases (TrxR): These are involved in the reduction of thioredoxin, which in turn reduces other proteins via cysteine thiol-disulfide exchange. - Selenoprotein P (SelP): While primarily involved in selenium transport, it also exhibits antioxidant properties.
