What are Some Examples of Regio- and Stereoselective Catalysis?
Several notable examples demonstrate the principles of regio- and stereoselective catalysis:
- Hydroformylation: This reaction adds a formyl group to alkenes. Catalysts like rhodium complexes with phosphine ligands can be tailored to favor either linear or branched aldehydes, showcasing regioselectivity.
- Asymmetric Hydrogenation: Using chiral ligands such as BINAP or chiral phosphines, catalysts can selectively hydrogenate prochiral alkenes to produce one enantiomer over the other, an example of stereoselectivity.
- CâH Activation: Catalysts that promote the selective activation of CâH bonds in complex molecules can be designed to target specific positions, a challenge that combines aspects of both regio- and stereoselectivity.
