What are Some Examples of Peptidomimetics in Catalysis?
Several examples demonstrate the application of peptidomimetics in catalysis:
Peptidomimetic Enzyme Inhibitors: Designed to inhibit specific enzymes by mimicking their natural substrates, these inhibitors can be used to regulate biochemical pathways. Catalytic Antibodies: Also known as abzymes, catalytic antibodies are engineered to mimic enzyme active sites, enabling them to catalyze specific reactions. Transition State Analogs: Peptidomimetics can be designed to resemble the transition states of specific reactions, thereby stabilizing these intermediates and enhancing the reaction rate.