Several indicators suggest that periodic maintenance is required:
1. Decreased Conversion: A drop in the conversion rate of reactants to products indicates catalyst deactivation. 2. Increased Pressure Drop: A rising pressure drop across the reactor suggests fouling or clogging. 3. Changes in Selectivity: Any shift in product distribution may signal catalyst degradation. 4. Unusual Temperatures: Deviations from normal operating temperatures may indicate issues with heat transfer or catalyst performance.