silylation

What Are Common Reagents Used in Silylation?

Common reagents used in silylation include chlorosilanes like trimethylsilyl chloride (TMSCl), as well as other silylating agents such as hexamethyldisilazane (HMDS) and trimethylsilyl trifluoromethanesulfonate (TMSOTf). These reagents react with hydroxyl or amino groups to form silyl ethers or silyl amines, respectively. The choice of reagent often depends on the specific requirements of the catalytic process and the nature of the substrate.

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