Optimizing solvent use involves several strategies: - Screening: Conducting experiments with different solvents to find the most effective one. - Co-Solvent Systems: Using a mixture of solvents to combine the benefits of each. - Solvent-Free Conditions: In some cases, reactions can be designed to occur without any solvent, reducing waste and cost. - Computational Methods: Predictive models can help in understanding solvent effects and guiding the selection process.
