The choice of drying agent depends on several factors:
Nature of the Catalyst: Some catalysts are more sensitive to water and may require more aggressive drying agents. Type of Reaction: Gas-phase reactions may benefit from molecular sieves, while liquid-phase reactions might require silica gel or calcium chloride. Solvent System: The solvent's compatibility with the drying agent must be considered to avoid unwanted reactions. Temperature and Pressure Conditions: Certain drying agents may lose efficacy under high temperatures or pressures.