Achieving chemo selectivity involves the careful design of catalysts that can interact preferentially with a specific functional group. This can be accomplished through various strategies:
Ligand Design: Tailoring the ligands in homogeneous catalysts to selectively bind to a particular substrate. Active Site Engineering: Modifying the active sites in heterogeneous catalysts to favor specific reactions. Reaction Conditions: Optimizing reaction conditions such as temperature, pressure, and solvent to enhance selectivity. Enzyme Catalysis: Using enzymes which are naturally highly selective catalysts.