How does solvent selection influence reaction pathways?
Solvent selection can dictate the predominant reaction pathway by stabilizing specific intermediates or transition states. For example, in acid-catalyzed reactions, polar protic solvents can stabilize carbocations, favoring pathways involving these intermediates. In contrast, non-polar solvents might favor pathways involving radical intermediates. Understanding these influences allows chemists to manipulate reaction conditions to achieve desired outcomes.
