How Does Online Monitoring Differ from Offline Monitoring?
Online monitoring involves real-time analysis of the reaction mixture without interrupting the reaction process. Techniques such as in-situ IR spectroscopy or online GC can provide continuous data, allowing for immediate adjustments and optimization. In contrast, offline monitoring requires sampling the reaction mixture at specific intervals and analyzing it separately. While online monitoring offers the advantage of real-time feedback, offline methods can provide more detailed and comprehensive data.