The selection of an appropriate monitoring technique depends on various factors, including the nature of the reaction, the state of the reaction mixture (gas, liquid, or solid), and the specific information required. For example, GC is suitable for gas-phase reactions, while HPLC is better for liquid-phase reactions. If the goal is to understand the molecular structure, NMR or MS may be preferable. It's often beneficial to use a combination of techniques to obtain a comprehensive understanding of the reaction.