L-Arginine serves as a key substrate in the catalytic cycle of the nitric oxide synthase enzyme. During the reaction, NOS converts L-Arginine into L-Citrulline and nitric oxide. The process occurs through the following steps: 1. L-Arginine binds to the active site of NOS. 2. The enzyme facilitates the transfer of electrons from NADPH, a cofactor, to the oxygen molecule. 3. This results in the formation of NO and L-Citrulline.
