ICP-MS involves ionizing the sample with an inductively coupled plasma and then using a mass spectrometer to separate and quantify the ions based on their mass-to-charge ratio. The process includes several steps: - Sample Introduction: The sample is introduced to the plasma, typically in liquid form. - Ionization: The plasma ionizes the sample components. - Mass Analysis: The ions are then directed into a mass spectrometer, where they are separated and detected.