How Does Catalysis Play a Role in RNA-Based Gene Editing?
Catalysis is fundamental to the mechanism of RNA-based gene editing. The Cas9 enzyme acts as a catalyst, facilitating the cleavage of DNA at specific sites. Enzymatic catalysts like Cas9 are highly specific and efficient, making them ideal for precise genetic modifications. The catalytic activity of Cas9 is driven by its ability to form a complex with guide RNA and the target DNA sequence, allowing for site-specific double-stranded breaks.
