How Does Catalysis Facilitate Asymmetric Synthesis?
Catalysis plays a pivotal role in asymmetric synthesis by enhancing the rate of reactions and improving selectivity. Catalysts, particularly chiral catalysts, are employed to induce asymmetry in the creation of chiral centers. These catalysts can be broadly classified into two categories:
- Homogeneous Catalysts: These are soluble in the reaction mixture and often involve chiral ligands. - Heterogeneous Catalysts: These are typically insoluble and can include chiral surfaces or supported catalysts.
