How does Bafilomycin function as a Catalytic Inhibitor?
Bafilomycin functions by binding to the V-ATPase enzyme, thereby inhibiting its catalytic activity. This enzyme is crucial for proton translocation across membranes, which is essential for processes like protein degradation, ion homeostasis, and vesicle trafficking. By inhibiting V-ATPase, Bafilomycin disrupts these processes, leading to altered cellular homeostasis.