How Does Active Site Geometry Affect Catalytic Activity?
The geometry of the active site is crucial for aligning reactant molecules in the optimal orientation for the reaction to occur. For instance, in enzyme catalysis, the active site is typically tailored to fit the substrate precisely, facilitating the reaction with minimal energy input. Similarly, in heterogeneous catalysis, the arrangement of metal atoms on the surface can create specific adsorption sites that favor the formation of intermediates, thereby accelerating the reaction.
