How Do You Select the Right Solvent for Catalysis?
Selecting the right solvent involves several considerations:
1. Polarity: Match the solvent polarity with the nature of the reactants and intermediates. 2. Protic vs. Aprotic: Protic solvents can donate hydrogen bonds, while aprotic solvents cannot. 3. Boiling Point: Choose a solvent with a suitable boiling point for the reaction temperature. 4. Compatibility: Ensure the solvent does not react with the catalyst or reactants. 5. Environmental and Safety Concerns: Prefer solvents that are non-toxic and environmentally benign.
