How Do Histone Modifications Interact with Other Epigenetic Mechanisms?
Histone modifications often work in concert with other epigenetic mechanisms such as DNA methylation and non-coding RNAs. For instance, certain histone modifications can recruit DNA methyltransferases to specific regions of the genome, leading to DNA methylation and gene silencing. Similarly, non-coding RNAs can guide histone-modifying enzymes to specific genomic loci, facilitating targeted modifications.
