regioselectivity

How Do Catalysts Achieve Regioselectivity?

Catalysts achieve regioselectivity through several mechanisms:
1. Steric Effects: Catalysts can impose steric hindrance, making certain positions on the substrate less accessible and thus directing the reaction to more accessible sites.
2. Electronic Effects: Catalysts can alter the electron density distribution in the substrate, making certain positions more reactive.
3. Template Effects: Some catalysts provide a template that holds the substrate in a specific orientation, ensuring that the reaction occurs at the desired position.

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